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>A novel antifungal strategy to inhibit Candida glabrata

Team Leader
Ashley Kidwell
Texas A&M University College of Medicine
Cell Biology and Genetics
ankidwel@tamu.edu

Project Type
Research

Who Can Join
Undergraduate Students

Project Description
Invasive mycoses are dangerous fungal infections of the blood or deep organs which carry a significant mortality of nearly 40%. Drug-resistant fungi such as Candida species and Nakaseomyces glabrata (formerly Candida glabrata) have been identified as the causative organisms at an alarming rate, prompting drug development efforts to identify novel antimycotic targets. To address this need, small molecule inhibitors of fungal phosphoinositide signaling have been established as a novel antimycotic strategy with activity against Nakaseomyces glabrata in vitro. This project will involve biochemistry, cell biology, and genetic techniques guided by the interest of the applicant within the scope of the project.

Team Needs
Relevant skills / what you will learn
-Molecular biology
-Molecular cloning
-Biochemistry
-Cell biology
-Microbiology

Special Opportunities
Frequent discussion on experimental design / project design and effective research presentation methods (abstract writing, poster design, elevator pitch, etc) guided by the interest of the applicant.

Categories: Research, STEM Education Research Leadership ProgramTags: Full

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