Team Leader
Sope Adeniji
Texas A&M University
Biology
odadeniji@tamu.edu
Project Type
Research
Who Can Join
Masters Students, Undergraduate Students
Project Description
With advanced sequencing technologies, researchers can now identify parts of the genome that are linked to beneficial traits or under selection pressure that help maintain species boundaries. However, genetic variation alone cannot fully explain all the differences in seen in traits across cells, individuals, populations, and species. Epigenetic mechanisms, such as DNA methylation, histone modifications, chromatin remodeling, and small RNAs, play an important role in identifying these differences because they alter how genes are expressed without changing the DNA sequence. These epigenetic changes have been implicated in conditions like cancer and cognitive developmental disorders in humans. Our study examines how DNA methylation is different between two closely related subspecies of Caulanthus (CAA and CAB) and their hybrids. These wild Brassicaceae populations have adapted to contrasting nutrient-poor soil conditions and distinct geographically isolated regions. While genetic variation have contributed to their unique identities, we hypothesize that epigenetic changes also plays a key role in their fitness to the environment. To test this, we are combining genome-wide methylation profiles with genetic and phenotypic data across hybrid generations. Our goal is to identify heritable epigenetic differences that may be linked to genetic variants and potentially associated with adaptation to nutrient-poor soil conditions. This research will help us understand more about how epigenetic processes contribute to gene regulation and plant survival in stressful environments.
Team Needs
basic knowledge of genes/genome
problem-solving
good communication
interest in and understanding of scientific literature
critical thinking
good interpersonal skills
Special Opportunities
research experience
molecular biology skills
bioinformatics skills
recommendation letter