Team Leader
Ahana Majumder
Texas A&M University Health Science Center
Medical Physiology
ahana.majumder@tamu.edu
Project Type
Research
Who Can Join
Masters Students, Undergraduate Students
Project Description
Duchenne muscular dystrophy (DMD) is an X-linked disorder affecting approximately 1 in 5000 males and is caused by mutations in the DMD gene, resulting in the loss of functional dystrophin. The absence of dystrophin leads to repeated contraction-induced muscle injury, which sustains a chronic immune response. The lymphatic system, essential for regulating local tissue inflammation, is impaired during DMD pathogenesis. In our laboratory, we employ a range of functional and molecular biology approaches to investigate the molecular mechanisms underlying the crosstalk between neuromuscular disease and lymphatic function. These studies are designed to inform the development of comprehensive therapeutic strategies to address the complex manifestations of DMD.
Team Needs
Interested in research and motivated to learn new techniques and skills.
Ability to contribute 6-8hrs per week.
Receive animal handling training.
Basic biology understanding and interest in learning about molecular biology, lymphatic biology, and physiology.
Special Opportunities
Significant contributors will earn authorship on resulting publications, undergraduate research presentation opportunities, potentially attend local conferences (Bryan/College Station), and will receive hands-on learning in laboratory techniques, including RNA and protein isolation, real-time quantitative PCR, immunofluorescence, and more!