Team Leader
Sydney Christensen
Texas A&M University
Biology, Genetics
schristensen7878@tamu.edu
Project Type
Research
Who Can Join
Undergraduate Students
Project Description
I’m working on an exciting project studying epigenetics and chromatin regulation using Drosophila melanogaster (fruit flies) as a model system. Specifically, I am investigating how histone modifications influence processes such as circadian rhythm, arousal, and wakefulness. A major focus of my work is on a group of recently discovered histone modifications. To explore their roles, I am using histone mutant fly lines and a combination of behavioral assays (such as sleep monitoring and survival testing) and molecular approaches (including Western blotting and immunohistochemistry).
In a related project, I am also using fruit flies to study histone mutations linked to human cancers. My goal is to understand how these mutations affect survival, longevity, and behavior, and to establish Drosophila as a model organism for investigating cancer-associated histone variants.
I'm looking for students to help with both of these areas of my research. Students will primarily work in the wet lab, but will also gain experience with basic computational data analysis. Students will have the opportunity to perform behavioral studies, fairly simple data analysis, and assist in molecular techniques, if they desire.
Team Needs
While any experience is fantastic, I am mainly looking for students who are excited and motivated to learn about and perform research. Sophomores, Juniors, and Seniors are preferred, and you must be willing to commit to the Fall and Spring semester. The number of hours can be flexible, but a willingness to commit to a general schedule is preferred.
Special Opportunities
This project will give students excellent research experience, and offers the potential to learn many different scientific techniques. In addition to hands-on research, students will also have the opportunity to develop skills for understanding scientific literature and operating in a research team, and will deepen their knowledge of the scientific research process. As students progress, they will have the opportunity to perform more independent research, contribute to publications, and present research at events like Student Research Week. This project would be an excellent way to begin gaining research experience or to try out new research, and will make a wonderful addition to applications for graduate, professional, or medical school, or job applications.