Team Leader
Mariana Bustamante
Texas A&M College Station
Biology
mnbustam@tamu.edu
Project Type
Research
Who Can Join
Graduate Students
Project Description
This project focuses on uncovering the neural basis of evolutionary behavior by reconstructing and comparing neural circuitry across different species. Using Drosophila (fruit flies) as a primary model, the research investigates how sexual selection has rewired neural circuits that drive divergence in complex behaviors, such as the evolution of varied courtship songs. To achieve this, the project utilizes advanced methodologies, including Expansion Microscopy to physically enlarge brain tissue and Light Microscopy to image fine cellular details, such as synapses. Participants will use Webknossos, an open-source software platform, to perform manual 3D neuro-annotation and tracing, ultimately allowing the lab to quantify and compare circuit-level modifications that have driven evolutionary changes.
Team Needs
We are searching for motivated undergraduate students who are passionate about neurobiology and evolutionary research to join our team! Our work focuses on the fascinating intersection of neural circuitry, behavioral evolution, and high-resolution 3D bio-imaging. We need reliable, detail-oriented individuals who are ready to thrive in a collaborative environment while also taking ownership of independent tasks.
What we value most is a positive, "can-do" attitude and an eagerness to master advanced tools like Webknossos. Because research is a dynamic process, we seek students who are punctual, communicative, and adaptable, as our tasks (ranging from precise manual neuro-annotation to complex behavioral analysis) evolve. If you are excited to help us uncover the fundamental neural "blueprints" that drive evolutionary changes in behavior, we want to hear from you!
Special Opportunities
Undergraduate students joining our lab will have the unique opportunity:
Neural Circuitry Reconstruction: You will learn the fundamental principles of mapping the nervous system, bridging the gap between microscopic cellular structures and complex animal behaviors.
3D Bio-imaging: Gain knowledge in cutting-edge techniques like Expansion Microscopy and Light Sheet Microscopy to visualize the brain in unprecedented detail.
Software Proficiency: Develop specialized skills in Webknossos, an industry-standard platform for manual 3D neuro-annotation and large-scale dataset visualization.
Hands-on Behavioral Analysis: Participate in research investigating how evolutionary pressures shape behaviors, such as the diverse and rhythmic courtship songs of Drosophila.
Contribute to Evolutionary Discovery: Work at the forefront of the field to help uncover the specific circuit-level modifications that drive behavioral evolution across species.